Naturex reviews fat burning data on Svetol

28 January 2008

Avignon, France-based Naturex, a natural ingredients developer, says that the recently-aquired Actif Innovants unit of herbal extracts supplier Berkem has completed and published a review on studies investigating the efficacy, mechanism of action and bioavailability of Svetol, a fat-burning water-soluble extract of decaffeinated green coffee beans.

On the basis of a new study and the scientific bibliography - on coffee and the active compounds in it - two different mechanisms of action were proposed and validated by Actifs Innovants to explain the weight management activity of Svetol. According to the firm, the ingredient acts as a fat burner by decreasing the intestinal glucose absorption and by inhibiting glucose-6-phosphatase in the liver.

The first approach is the inhibition of glucose absorption from the digestive tract. This has been validated in a clinical trial on humans. 400mg Svetol supplementation per day for 40 days significantly reduces the post-load glycemia after an oral glucose tolerance test, without any change in the pre-load glycemia. The trial results have been published in the peer-reviewed journal, NUTRAfoods.

This article is accessible to registered users, to continue reading please register for free.  A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.

Login to your account

Become a subscriber

 

£820

Or £77 per month

Subscribe Now
  • Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
  • Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
  • Daily roundup of key events in pharma and biotech.
  • Monthly in-depth briefings on Boardroom appointments and M&A news.
  • Choose from a cost-effective annual package or a flexible monthly subscription
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed

Chairman, Sanofi Aventis UK





Today's issue

Company Spotlight