Avignon, France-based Naturex, a natural ingredients developer, says that the recently-aquired Actif Innovants unit of herbal extracts supplier Berkem has completed and published a review on studies investigating the efficacy, mechanism of action and bioavailability of Svetol, a fat-burning water-soluble extract of decaffeinated green coffee beans.
On the basis of a new study and the scientific bibliography - on coffee and the active compounds in it - two different mechanisms of action were proposed and validated by Actifs Innovants to explain the weight management activity of Svetol. According to the firm, the ingredient acts as a fat burner by decreasing the intestinal glucose absorption and by inhibiting glucose-6-phosphatase in the liver.
The first approach is the inhibition of glucose absorption from the digestive tract. This has been validated in a clinical trial on humans. 400mg Svetol supplementation per day for 40 days significantly reduces the post-load glycemia after an oral glucose tolerance test, without any change in the pre-load glycemia. The trial results have been published in the peer-reviewed journal, NUTRAfoods.
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