- The US National Cancer Institute has started enrolling patients with brain tumors into its Phase I/II trial of Alkermes' RMP-7 in combination with standard-dose carboplatin. RMP-7 is a drug which transiently increases the permeability of the blood-brain barrier, allowing a higher concentration of carboplatin at the lesion site and hopefully increased efficacy. Several Phase II studies of RMP-7 plus carboplatin are ongoing across the USA and Europe.
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