New cancer drug trials in USA/UK

20 April 2008

A new class of anticancer drug is undergoing trials in the UK and the USA, the UK Institute of Cancer Resea-rch has announced.

The drug, GDC-0941, was discovered by UK biotechnology company Piramed based upon a chemi-cal series identified by an earlier collaboration involv-ing the institute, the US Ludwig Institute for Cancer Research, Cancer Research UK and Japan-based Yamanouchi Pharmaceutical (now Astellas Pharmaceutical).

The drug is highly effective against PI 3-kinase, a key intracellular enzyme involved in a wide range of cancers, both in monotherapy and also in combination with certain approved and experimental therapies.

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