NICE recommends Rybrevant approval for NHS use

8 May 2026

The UK’s National Institute for Health and Care Excellence (NICE) has recommended approval for US healthcare giant Johnson & Johnson’s (NYSE: JNJ) Rybrevant (amivantamab).

Rybrevant with carboplatin and pemetrexed can be used during a managed access period for untreated advanced non-small cell lung cancer (NSCLC) with activating epidermal growth factor receptor (EGFR) exon 20 insertion mutations in adults, the health technology assessor’s final draft guidance stated.

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