Novartis vacc beats Menactra in Ph III trials
Swiss drug major Novartis reports its candidate Menveo (MenACWY-CRM), indicated to treat four strains of meningitis, performed better in Phase III trials than the current equivalent treatment, Menactra (meningococcal polysaccharide diphtheria toxoid conjugate vaccine) made by Sanofi-Pasteur, the vaccines unit of French drug major Sanofi-Aventis.
The candidate is indicated to treat the meningococcal strains A, C, W-135 and Y. Results of the head-to-head trial showed that Menveo generated higher levels of antibodies than Menactra in adolescents aged 11 to 18 years, particularly against meningitis Y, with 81% of candidates generating a protective immune response, as opposed to 54% with Menactra, according to the firm.
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