NXL104/ceftazidime enters Ph II cUTI trial
French antibiotics developer Novexel says that its most advanced injectable antibacterial, which combines its broad-spectrum beta-lactamase inhibitor, NXL104, with the well-established cephalosporin antibiotic, ceftazidime, has entered Phase II trials.
The initial mid-stage study of NXL104/ceftazidime will be in hospitalized patients with complicated urinary tract infections. From national databases providing hospital patient discharge data, Novexel estimates that more than 1.1 million patients were treated for cUTIs in the hospital in the seven major pharmaceutical markets last year. The results of this study are expected in late 2009.
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