ONYX-015 Enters Phase II
Onyx Pharmaceuticals has started Phase II studies of itsgenetically-engineered adenovirus, ONYX-015, in patients with refractory head and neck tumors. The trials will be conducted at 12 sites in the USA, UK and Canada. The company is also planning a trial of the adenovirus, which replicates in and kills cells deficient in the p53 tumor suppressor gene, in combination with chemotherapy.
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