Ophthotech in-licenses volociximab for AMD

14 January 2008

Ophthotech in-licenses volociximab for AMD

New Jersey-based firm Ophthotech has in-licensed exclusive worldwide rights to the candidate monoclonal antibody drug, volociximab, from fellow US companies Biogen Idec and PDL BioPharma. The deal entitles Ophthotech to develop and commercialize the compound for the treatment of diseases of the back of the eye, including age-related macular degeneration.

Volociximab, which will continue to be developed for solid tumor cancers by Biogen and PDL under their 2005 agreement (Marketletters passim), targets the alpha-5-beta-1 integrin protein, known to be a key factor in angiogenesis. Under its license, Ophthotech will focus on assessing the molecule in AMD, a condition characterized by the aberrant growth of blood vessels.

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