Peregrine Pharmaceuticals has reported the issuance of a US patent that further strengthens the company's intellectual property in the field of phospholipid-targeting agents for the treatment of life-threatening diseases. The new patent grants composition-of-matter claims that cover multiple formulations of phosphatidylethanolamine-binding agents attached to a wide variety of antiviral agents. PE belongs to the aminophospholipid family that also includes phosphatidylserine, the target for Peregrine's monoclonal antibody bavituximab that is in a clinical trial for hepatitis C and in preclinical studies for HIV and other viral infections. This new patent follows issuance last year of broad methods patents covering use of PE-binding agents in anti-viral applications.
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