US biopharmaceutical firm Peregrine Pharmaceuticals says it has licensed worldwide exclusive rights to a novel anti-angiogenesis technology from the University of Texas' Anderson Cancer Center. The deal transfers development and commercialization rights to all forms of "nicked" beta-2-glycoprotein (BSGP1) to the company for examination in various cancer indications.
Previous research, published last year in the Annals of Surgical Oncology, indicates that BSGP1 has considerable anticancer potential. In one animal model of bladder cancer, for example, the drug's therapeutic activity, mediated via its inhibition of endothelial cell proliferation, reduced tumor growth around 96%. Financial terms of the license agreement were not provided.
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