AstraZeneca prostate cancer drug fails in Phase III trial
AstraZeneca has suffered another setback in its late-stage R&D pipeline after its candidate prostate cancer drug zibotentan failed in a Phase III trial.
A 10mg daily oral dose of zibotentan failed to meet the primary endpoint of improved overall survival compared to standard care in the trial (Study 14), which included 594 patients with metastatic, castration-resistant prostate cancer.
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