German family-owned drug major Boehringer Ingelheim and US pharma major Eli Lilly (NYSE: LLY) have enrolled the first patient in a new cardiovascular and renal outcomes trial for Trajenta (linagliptin) in type 2 diabetes.
The CARMELINA (CArdiovascular safety and RenalMicrovascular outcomE with LINAgliptin in patients with Type 2 Diabetes mellitus at high vascular risk) trial will investigate the once-daily dipeptidyl peptidase-4 (DPP-4) inhibitor, linagliptin, on cardiovascular and renal microvascular outcomes in adults with type 2 diabetes at risk of cardiovascular and renal events.
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