
India's Bharat Biotech has recently completed the Phase III trials of its COVID-19 intranasal vaccine BBV154 and submitted the data to the Drug Controller General of India (DCGI) for approval both as a primary two-dose vaccine, and a heterologous booster dose. However, the company has not yet made clinical trial results publicly available.
BBV154 could be the second approved intranasal vaccine for COVID-19 in the world. Based on the novel adenovirus vector, BBV154 is an intranasal vaccine for COVID-19 which stimulates a broad immune response neutralizing IgG, mucosal IgA, and T cell responses, he said. Most importantly, it is effective for blocking both infection and transmission of the novel coronavirus.
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