
Canada’s AEterna Zentaris (TSX: AEZ) and Orient EuroPharma (OEP) have signed an exclusive license agreement between the company and Cyntec, an affiliate of OEP for its lead anti-cancer compound, Zoptrex (zoptarelin doxorubicin), for the initial indication of endometrial cancer, for Taiwan and nine countries in Southeast Asia.
Zoptrex, a novel synthetic peptide carrier linked to doxorubicin as a New Chemical Entity (NCE), is currently in a fully-enrolled Phase III clinical trial in endometrial cancer. The Company expects to complete the Phase III clinical trial in the third quarter of 2016 and, if the results of the trial warrant doing so, to file a New Drug Application for Zoptrex in the first half of 2017.
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