Cytokinetics’ aficamten bests beta blocker in head-to-head trial

1 September 2025

Cytokinetics (Nasdaq: CYTK) has taken a major step forward with aficamten, its experimental therapy for obstructive hypertrophic cardiomyopathy. In a Phase III trial unveiled at the European Society of Cardiology congress and published in the New England Journal of Medicine, aficamten outperformed metoprolol, the beta blocker long used as the standard treatment.

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