
Cytokinetics (Nasdaq: CYTK) today announced that the European Commission (EC) has approved Myqorzo (aficamten) for the treatment of symptomatic (New York Heart Association, NYHA, class II-III) obstructive hypertrophic cardiomyopathy (oHCM) in adult patients.
Myqorzo is an allosteric and reversible inhibitor of cardiac myosin motor activity. In patients with oHCM, myosin inhibition with Myqorzo reduces cardiac contractility and consequently, left ventricular outflow tract (LVOT) obstruction.
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