EyePoint tanks despite touting positive results for Duravyu
USA-based ophthalmic diseases specialist EyePoint Pharmaceuticals (Nasdaq: EYPT) today announced top-line results from LUGANO, the first pivotal Phase III clinical trial for Duravyu (vorolanib intravitreal insert) for the treatment of wet age-related macular degeneration (wet AMD).
EyePoints’ shares plummeted 71% to $4.28, as the company noted Duravyu was non-inferior to on-label aflibercept (nominal p-value = 0.0096) in an ad hoc analysis excluding a 4% asymmetric cohort (9 of 211 patients) who experienced vision loss (≥ 15 letters) unrelated to wet AMD.
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