J&J and Pfizer drop bapineuzumab development for Alzheimer's
There was disappointing - though not really unexpected - news yesterday for US health care giant Johnson & Johnson (NYSE: JNJ) and global drugs behemoth Pfizer (NYSE: PFE), when the companies announced that Phase III clinical development of their investigational drug bapineuzumab intravenous (IV) in mild-to-moderate Alzheimer's disease is being discontinued. The co-primary clinical endpoints, change in cognitive and functional performance compared to placebo, were not met in the studies.
Janssen Alzheimer Immunotherapy (Janssen AI), a subsidiary of Johnson & Johnson, is a partner with Pfizer in the Alzheimer's Immunotherapy Program (AIP). The Joint Steering Committee for the AIP has decided to discontinue the development of bapineuzumab IV in mild-to-moderate Alzheimer's disease based on the co-primary clinical endpoints not being met in the Janssen AI-led Studies 301 and 302.
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