Karyopharm research and financing developments

24 March 2026

Karyopharm Therapeutics (Nasdaq: KPTI) today reported top-line results from its Phase III SENTRY Trial in myelofibrosis that met the first co-primary endpoint, demonstrating statistically-significant improvement in spleen reduction volume.

Karyopharm also announced that it has entered into a securities purchase agreement with RA Capital Management for a private placement that is expected to result in gross proceeds of approximately $30 million.

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