
Shares of US drugmaker Karyopharm Therapeutics (Nasdaq: KPTI) leapt more than 36% to $8.90 by close of trading on Wednesday, after it announced that the US Food and Drug Administration had granted accelerated for its blood cancer drug Xpovio (selinexor). The stock gained a further 5.2% to $9.36 in after-hours trading.
The FDA granted approval for selinexor in combination with dexamethasone for adult patients with relapsed or refractory multiple myeloma (RRMM) who have received at least four prior therapies and whose disease is refractory to at least two proteasome inhibitors, at least two immunomodulatory agents, and an anti-CD38 monoclonal antibody.
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