Merck & Co/Cardiome's Brinavess shows superiority to amiodarone in Ph III AF trial; Zostavax safety confirmed

18 May 2010

US drug giant Merck & Co says that a new Phase III study with Brinavess (vernakalant) intravenous, an investigational compound being developed in the European Union by its subsidiary Merck Sharp & Dohme to treat atrial fibrillation, showed that the drug was superior to amiodarone injection, in converting patients' heart rate from atrial fibrillation (AF) to sinus rhythm (SR) within 90 minutes of the start of administration.

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