In a second disappointment from the agency this week, US drugs behemoth Pfizer (NYSE: PFE) Ltd expressed concern that guidance from the UK’s drug watchdog National Institute for Health and Clinical Excellence (NICE) does not recommend its Inlyta (axitinib), a new treatment for patients with advanced renal cell carcinoma (commonly known as kidney cancer) who are no longer receiving clinical benefit from treatment with sunitinib or a cytokine.
This final draft guidance comes just a day after the firm also received a negative preliminary guidance for its lung cancer drug Xalkori (crizotinib; The Pharma Letter March 27).
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