NICE draft recommendation against lenacapavir for PrEP slammed

10 September 2026

The British Association for Sexual Health and HIV (BASHH) is deeply disappointed by the UK’s National Institute for Health and Care Excellence’s (NICE) draft recommendation not to approve lenacapavir for HIV prevention in the National Health Service (NHS) in England.

US antivirals specialist Gilead Sciences’ (Nasdaq: GILD) lenacapavir, trade name Yeztugo, is a long-acting option for HIV prevention that requires a 6-monthly injection. Technologies like this have the potential to broaden choice and help address some of the key barriers that prevent people from accessing or consistently using existing forms of PrEP.

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