Positive mid-stage data for new Parkinson’s dyskinesia drug

6 March 2025

Polish drugmaker Celon Pharma (WSE: CLN) has announced positive results from a Phase II trial of CPL’36, an experimental oral treatment for levodopa-induced dyskinesia (LID) in Parkinson’s disease.

The trial of the once-daily PDE10A inhibitor met its primary endpoint, demonstrating significant reductions in unwanted movements linked to Parkinson’s medications. The low dose group saw a 12.3-point reduction, while the high dose group benefitted from a 13.58-point decrease.

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