Positive top-line Phase III results for Otsuka's ADHD candidate
Japanese drugmaker Otsuka (TYO: 4578) today announced positive results of two, six-week, Phase III clinical trials that evaluated the efficacy, safety, and tolerability of centanafadine for the treatment of adolescents and children with attention-deficit/hyperactivity disorder (ADHD).
Otsuka says that its centanafadine is a first-in-class norepinephrine, dopamine, and serotonin reuptake inhibitor. The Japanese firm gained rights to the compound along with its acquisition of privately-held US firm Neurovance in 2017, for which it paid $100 million upfront with $150 million contingent on developmental milestones.
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