Repligen plunges as bipolar drug flops in Ph IIb trial
USA-based Repligen (Nasdaq: RGEN) saw its shares plummet 29.1% to $3.48 by mid-afternoon trading yesterday, after the company announced results of a Phase IIb clinical trial of RG2417, an oral formulation of uridine, in patients with bipolar depression. The study did not demonstrate a statistically-significant improvement in the symptoms of depression in all patients receiving RG2417 when compared to placebo over the eight-week treatment period.
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