Roche’s petrelintide shows promise in Phase II obesity trial
Swiss pharma Roche (ROG: SIX) reported positive Phase II results for its investigational amylin analog petrelintide, showing meaningful weight loss and a placebo-like tolerability profile in people living with overweight and obesity.
In the ZUPREME-1 study, patients receiving once-weekly petrelintide achieved up to 10.7% mean body weight reduction at week 42 compared with 1.7% with placebo. Roche said the trial met its main endpoint and showed statistically significant weight loss across all tested doses.
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