In a second licensing deal this year, Japan’s largest drugmaker Takeda Pharmaceutical (TSE: 4502) has entered into an exclusive collaboration with USA-based Intra-Cellular Therapies (ITI) to develop and commercialize selective phosphodiesterase type 1 (PDE1) inhibitors, discovered by the latter and in preclinical testing, for the treatment of cognitive impairment associated with schizophrenia. This agreement is targeted worldwide, but ITI has retained the option to co-promote with Takeda in the USA.
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