Japan’s largest drugmaker Takeda Pharmaceutical (TYO: 4502) has decided not to commercialize peginesatide (formerly known as Hematide) in Japan. The drug was licensed from the USA’s Affymax (Nasdaq: AFFY) in 2006, in a deal that earned the US firm $150 million upfront with the potential to receive $345 million in developmental and regulatory milestone, some of which have since been paid on clinical progress into Phase III.
Peginesatide is an investigational therapy for use in the treatment of patients with anemia due to chronic kidney disease (CKD). Takeda and Affymax will explore other options for the commercialization rights for this product in the Japanese market, including potentially licensing it out to a third party.
Companies will continue to work on US and EU regulatory filing
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