Trial miss for StemRIM and Shionogi’s redasemtide

9 September 2026

Shionogi (TYO: 4507) today released the results of an additional Phase II clinical trial in patients with dystrophic epidermolysis bullosa and a global Phase II clinical trial in patients with acute ischemic stroke for redasemtide (a peptide drug created from HMGB1; S-005151), a regeneration-inducing medicine candidate in-licensed from fellow Japan-based StemRIM.

Shares of Shionogi closed up 1.8% at 2,846 yen following the announcement.

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