A combination of two diabetes drugs, metformin and rosiglitazone (the active ingredient of GlaxoSmithKline’s Avandia, now virtually withdrawn from the market because of safety concerns), was more effective in treating youth with recent-onset type 2 diabetes than metformin alone, a study funded by the National Institutes of Health (NIH) has found. Adding an intensive lifestyle intervention to metformin provided no more benefit than metformin therapy alone.
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