Vivus findings show greater risk of birth defects with Qnexa ingredient
USA-based drug developer Vivus (Nasdaq: VVUS) has released top-line preliminary results from its retrospective study of medical claims data on oral clefts (OC) associated with in utero exposure of topiramate, an active ingredient of its obesity drug candidate Qnexa (phentermine and topiramate), showing an increased risk of this birth defect. The news caused Vivus shares to fall 8.7% to $9.50.
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