AstraZeneca study of Brilinta meets primary endpoint
Anglo-Swedish drug major AstraZeneca (LSE: AZN) has announced its PEGASUS-TIMI 54 study of its already marketed drug Brilinta (ticagrelor) has met its primary endpoint.
It assessed Brilinta tablets at either 60mg twice daily or 90mg twice daily plus low-dose aspirin for the secondary prevention of atherothrombotic events in patients who had experienced a heart attack one to three years prior to study start. The primary efficacy endpoint was a composite of cardiovascular (CV) death, myocardial infarction (MI) or stroke.
The PEGASUS-TIMI 54 study investigated two different doses of Brilinta on a background of low dose aspirin versus placebo plus low dose aspirin, in patients aged 50 and over with a history of heart attack and one additional CV risk factor. No unexpected safety issues were encountered.
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