AstraZeneca tremelimumab trial fails to meet endpoints

1 March 2016

AstraZeneca (LSE: AZN) has published disappointing results from a Phase IIb cancer drug trial, with the news causing the firm's shares to decline 2.3% to £41.07 in yesterday's trading.

Researchers said the DETERMINE trial on tremelimumab as a monotherapy did not meet its primary endpoint of improving overall survival rates in mesothelioma patients with no currently approved treatment options in the second-line setting.

They stressed, however, that the drug remains a key component of the company’s immuno-oncology combination strategy across multiple tumour types

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