First-in-class targeted therapy has potential in colon cancer

4 January 2024

Germany’s Merck KGaA (MRK: DE) has announced a licensing agreement with New York-based small molecule developer Inspirna.

The deal relates to a first-in-class SLC6A8 blocker, ompenaclid, and will include other similar follow-on compounds.

Ompenaclid is currently being evaluated in a Phase II trial for the second-line treatment of certain people with advanced or metastatic colorectal cancer (mCRC).

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