Genfit plans spending cut after ending VS-01 program in ACLF
French biopharma Genfit (Nasdaq and Euronext: GNFT) has announced its decision to discontinue its VS-01 program in acute-on-chronic liver failure (ACLF) and reprioritize the development of VS-01 to urea cycle disorder (UCD).
Genfit’s decision follows the occurrence of a peritonitis case reported as serious adverse event (SAE) in the UNVEIL-IT trial of VS-01 in patients with ACLF grades 1, 2 or 3a and ascites and subsequent review and feedback from the independent data monitoring committee.
The committee concluded that the trial could continue but required additional data and monitoring.
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