Incyte releases new data from Phase IIIb trial of Opzelura in dermatitis

28 October 2025

US biopharma company Incyte (Nasdaq: INCY) has announced new data from the Phase IIIb TRuE-AD4 study evaluating the efficacy and safety of Opzelura (ruxolitinib cream) in adults with moderate atopic dermatitis (AD) who had an inadequate response, intolerance or contraindication to topical corticosteroids (TCSs) and topical calcineurin inhibitors (TCIs).

These data were e presented during the Systemic and New Therapies for Atopic Dermatitis session on October 26.

Opzelura is already approved and marketed for the treatment of non-segmental vitiligo. Incyte has guided for Opzelura 2025 sales of $630 million to $670 million. Second-quarter 2025 net sales reaching $164 million, a 35% year-over-year increase.

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