Mixed results for AD agitation drug unsettle Lundbeck investors

2 May 2017

Danish CNS specialist Lundbeck (LUND: CO) and Japanese drug major Otsuka Pharmaceutical (TYO: 4578) have announced mixed results from two Phase III dementia studies.

The companies are evaluating the efficacy, safety and tolerability of brexpiprazole, which was discovered by Otsuka, as a treatment for agitation in patients with Alzheimer’s disease.

The primary endpoint of both trials was change from baseline in a commonly-used assessment test for agitation.

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