Novartis' midostaurin achieves 60% response rate in advanced systemic mastocytosis

30 June 2016
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Swiss pharma giant Novartis (NOVN: VX) has announced the publication of data on PKC412 (midostaurin) demonstrating an overall response rate of 60% in patients with advanced systemic mastocytosis (SM).

This encouraging reaction, defined as complete or partial resolution of organ damage, was noted in a pivotal Phase II study, the largest and longest-running prospective trial in advanced SM, is good news for patients with this rare disease with a poor prognosis.

Currently, there is no approved treatment for the majority of patients.

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