Danish pharma major Novo Nordisk (NOV: N) and privately-held Californian firm Deep Apple Therapeutics have announced a research collaboration and exclusive worldwide license agreement.
The collaboration is aimed at discovering, developing and commercializing oral small molecule therapeutics directed at a novel non-incretin G-protein coupled receptor (GPCR) target for cardiometabolic diseases, including obesity.
Under the terms of the deal, Deep Apple will discover and optimize compounds using its proprietary drug discovery platform, which combines machine-learning-powered virtual screening with structural biology enabled by cryo-electron microscopy (cryo-EM) to improve speed, quality and novelty in lead generation and optimization.
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