Pfizer scraps GLP-1-RA candidate lotiglipron

26 June 2023

Pharma giant Pfizer (NYSE: PFE) was trading 4% lower at lunchtime on Monday.

This followed the announcement that the company will continue to progress only one of its oral late-stage glucagon-like peptide-1 receptor agonist (GLP-1-RA) candidates in obesity and type 2 diabetes mellitus (T2DM).

Pfizer will press on with the development of danuglipron in the hope it can provide competition in these conditions for semaglutide, Novo Nordisk’s (NOV: N) big-selling GLP-1 RA which is marketed as Ozempic and Wegovy.

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