Phase III data first to show DFS improvement in early resected ALK-positive NSCLC

18 October 2023

Swiss pharma giant Roche (ROG: SIX) has announced results from the primary analysis of the Phase III ALINA study.

The study results showed that Alecensa (alectinib) reduces the risk of disease recurrence or death by 76% compared with platinum-based chemotherapy in people with completely resected stage IB to IIIA anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC).

A clinically-meaningful improvement of central nervous system disease free survival was also observed.

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