Phase III trial success for Amgen's romosozumab

22 February 2016

US biotech giant Amgen (Nasdaq: AMGN) and Belgium's UCB (Euronext Brussels: UCB) have announced successful top-line results from the Phase III placebo-controlled fracture study in postmenopausal women with osteoporosis (Frame).

The study met all primary endpoints by reducing the incidence of new spinal fractures through months 12 and 24 in post-menopausal women with osteoporosis treated with romosozumab.

Amgen and UCB now plan to discuss the Frame results with global regulators in anticipation of a potential filing as early as this year.

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