Positive new trial data for Xultophy
New Phase IIIb trial (DUAL VII) results with Xultophy (IDegLira), which was approved by the US Food and Drug Administration last month, were presented today.
The open-label trial investigated the efficacy and safety of Danish diabetes giant Novo Nordisk’s (NOV: N) Xultophy compared with insulin glargine U100 in combination with insulin aspart at all main meals, after 26 weeks of treatment in 506 adults with type 2 diabetes.
The trial successfully achieved its objective by demonstrating that treatment with Xultophy is non-inferior to insulin glargine U100 in combination with insulin aspart with regards to lowering of HbA1c. From a mean baseline HbA1c of 8.2%, both patient groups reached a similar HbA1c level of 6.7% after 26 weeks of treatment. At the end of the trial, people treated with Xultophyrequired 40.1 units compared to a total of 84.6 units of insulin for people treated with insulin glargine U100 in combination with insulin aspart. 3
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