Results from Merck & Co study show 99% effectiveness of elbasvir/grazoprevir for hepatitis C

14 April 2016

Findings from a head-to-head study conducted by US pharma Merck & Co (NYSE: MRK) have shown almost complete efficacy of elbasvir/grazoprevir in the treatment of chronic hepatitis C.

A Phase III trial compared the combination to a regimen of sofosbuvir tablets plus peginterferon and ribavirin in both treatment-naïve and treatment-experienced patients with chronic hepatitis C (HCV) genotype 1 or 4 infection.

The efficacy endpoint of sustained virologic response (SVR) 12 weeks after the completion of therapy, SVR12 – considered virologic cure – was achieved in 128 out of 129 of patients receiving elbasvir/grazoprevir for 12 weeks.

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