Taiwan listing boosts market for oral XPO1 blocker

13 February 2025

Antengene (HK: 6996) has announced that its multiple myeloma treatment, Xpovio (selinexor), will be included in Taiwan’s National Health Insurance (NHI) reimbursement scheme.

The approval covers use of the XPO1 inhibitor, in combination with bortezomib and dexamethasone, for adults with relapsed or refractory multiple myeloma who have received at least two prior therapies.

Xpovio is the first approved oral therapy of its kind. By blocking the XPO1 protein, the drug helps retain tumor suppressor proteins in the nucleus, leading to anti-tumor effects.

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