Trial disappointment for lupus candidate anifrolumab

31 August 2018
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Cambridge, UK-based AstraZeneca (LSE: AZN) and its biologics arm MedImmune have announced a Phase III trial failure for systemic lupus erythematosus (SLE) candidate anifrolumab.

The result comes as a severe disappointment for lupus patients, after the candidate passed its Phase II test in 2015 with flying colors.

The late-stage trial did not meet the primary endpoint of a statistically-significant reduction in disease activity in patients with SLE, as measured by a commonly-used scale.

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