PharmaMar's Irvalec enters Ph I/II study with Tarceva
Spanish biotechnology firm PharmaMar, a part of the Zeltia Group, has initiated a Phase I/II study of Irvalec, a synthetic depsipeptide, with Roche's Tarceva (erlotinib) in non-small cell lung cancer.
The study will determine the safety and tolerability of the drug and will establish dose-limiting toxicity, as well as the recommended dose. Recruitment will last 18 months, the firm noted.
Irvalec, which is derived from the PharmaMar development program of marine-origin compounds, is a new drug with antiproliferative activity against a wide range of tumors, including breast, colon, pancreas, lung and prostate.
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