Danish drugmaker TopoTarget AS and USA-based CuraGen have initiated treatment in a new Phase Ib/II trial evaluating their histone deacetylase inhibitor, PXD101, in combination with Millennium/Ortho Biotech's Velcade (bortezomib) in multiple myeloma, a deadly form of blood cancer. Preliminary results from this proof-of-concept study are expected by the middle of next year.
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