UK firm Phico Therapeutics says it has been granted a Wellcome Trust Strategic Translational Award totalling just over GBP1.0 million ($1.4 million) to cover Phase I and II trials of its lead candidate SASPject PT1.2 for decolonization of methicillin-resistant Staphylococcus aureus and S. aureus. PT1.2 is based on a new class of antibacterial proteins called SASPs which bind to bacterial DNA resulting in rapid "speed of kill." If successful, the agent will provide a major new weapon in the fight against MRSA and other bacterial infections, according to the company.
Ted Bianco, director of technology transfer at the Wellcome Trust, commented: "there is an urgent need to develop innovative ways to manage the transmission of antibiotic-resistant bacteria in the hospital and care-home environments. The approach being taken by Dr Fairhead and colleagues is imaginative and original. If successful, this technology may provide an important new tool in the fight against MRSA and other pathogenic bacteria."
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